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The differential diagnosis for congenital corneal opacity can be remembered using the pneumonic STUMPED:

S clerocornea

T ears in Descemet’s membrane or birth trauma

U lcer or infection

M ucopolysaccharidosis (MPS)

P eters’ anomaly

E ndothelial dystrophy, congenital hereditary (CHED)

D ermoid

Developmental anomaly of the cornea

Defective mesodermal migration during embryogenesis, resulting in tissue resembling sclera rather than clear corneal stroma

Can be autosomal dominant, recessive, or sporadic

Has been associated with the 22q11.2 deletion syndrome

Opacified cornea present since birth

Usually bilateral but can be unilateral

Opacification of the cornea with the peripheral cornea more opacified than the central cornea ( Thomas Sabo WomenBead Pug Karma Beads 925 Sterling Silver blackened Zirconia black K016469112 FrPTj5jh
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May have fine blood vessels

Glaucoma

Evaluation by a genetic specialist to look for associated congenital anomalies

If the central cornea is clear, it can be associated with cornea plano and a high refractive error.

Penetrating keratoplasty should be considered if the central visual axis is involved and the posterior segment is relatively normal.

Visual outcome with or without keratoplasty depends on the presence of other ­ocular and systemic abnormalities.

Binenbaum G, McDonald-McGinn DM, Zackai EH, et al. Sclerocornea associated with the chromosome 22q11.2 deletion syndrome. Am J Med Genet A. 2008;146(7):904–909.

Doane JF, Sajjadi H, Richardson WP. Bilateral penetrating keratoplasty for sclerocornea in an infant with monosomy 21. Case report and review of the literature. Cornea . 1994;13(5):454–458.

Kim T, Cohen EJ, Schnall BM, et al. Ultrasound biomicroscopy and histopathology of sclerocornea. Cornea . 1998;17(4):443–445.

FIGURE 2-1. Descemet’s membrane: sclerocornea. The corneal opacification is more severe peripherally than centrally.

Trauma to the cornea during vaginal delivery resulting in tears in Descemet’s membrane

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Anne Weil
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“This book is a must-have for anyone who wants to create something functional and beautiful from the heart without investing in expensive tools, endless supplies, or clunky machines. You only need your hands, some wool and the projects in this beautiful book. I’m not a knitter but after seeing the stunning photos of Anne’s projects and reading her supportive words, I’m definitely giving Knitting Without Needles a try!”

—Holly Becker, author and founder of Rhodium On Sterling Silver Clear Cz Cubic Zirconia Dot Earring Cuff / Ear Cuffs Wrap EK4qQ2

Drop your knitting needles and roll up your sleeves! Arm and finger knitting have taken the craft world by storm, and in Knitting Without Needles: A Stylish Introduction to Finger and Arm Knitting (Potter Craft; $19.99; on-sale 9/1/15), Anne Weil shares stylish patterns that are incredibly DIY-able, with easy-to-follow instructions and step-by-step photos that yield gorgeous and sophisticated results.

Drop your knitting needles and roll up your sleeves! Knitting Without Needles: A Stylish Introduction to Finger and Arm Knitting

Your go-to resource for a revolutionary craft, Knitting Without Needles covers two popular techniques: Finger knitting, a form of weaving loops of yarn through one another on your hand to create long chains of knit fabric; and arm knitting, which uses your forearms to loop strands of yarn into chunky knits. These techniques are super easy and provide near-instant gratification. Imagine knitting a chunky scarf in just 45 minutes!

Knitting Without Needles

Complete beginners and experienced knitters alike can make the fabulous projects in Knitting Without Needles , from lavish home decor to stylish accessories you’ll love to wear to fun projects to make with kids. All you need is yarn and your own two hands (literally) to create a cozy cabled blanket, a pom-pom trimmed hat, a pouf for your living room, tiny baby booties, and plenty of other must-have items.

On Saturday, August 25, 2018 join cyclists from around the region for a cycling event around Chautauqua Lake followed by a post ride party at Webb’s Captain’s Table in Mayville, NY.

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